Published Planning Grant Research

The Institute for Successful Longevity awards planning grants to promote interdisciplinary research among researchers at Florida State University. See below for published research projects that have resulted from these grants.


Kiran S, Thilanka U, Xue Y, Sang QA. Polystyrene Micro- and Nanoplastic Exposure Triggers an Activation and Stress Response in Human Astrocytes. Int J Mol Sci. 2025 Nov 21;26(23). doi: 10.3390/ijms262311273. PubMed PMID: 41373431; PubMed Central PMCID: PMC12692081.
https://pubmed.ncbi.nlm.nih.gov/41373431/

Mahmud F, Sarker DB, Jocelyn JA, Sang QA. Molecular and Cellular Effects of Microplastics and Nanoplastics: Focus on Inflammation and Senescence. Cells. 2024 Oct 29;13(21). doi: 10.3390/cells13211788. Review. PubMed PMID: 39513895; PubMed Central PMCID: PMC11545702.
https://pubmed.ncbi.nlm.nih.gov/39513895/

Sheffler, J. L., Kiosses, D. N., He, Z., Arjmandi, B. H., Akhavan, N. S., Klejc, K., & Naar, S. (2023). Improving Adherence to a Mediterranean Ketogenic Nutrition Program for High-Risk Older Adults: A Pilot Randomized Trial. Nutrients, 15(10), 2329.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223314/

Sheffler, J.L., Burchard, V., Pickett, S.M. (2023). Adverse childhood experiences and poor sleep quality in older adults: The influence of emotion regulation. Journal of Gerontology: Medical Sciences.
https://pubmed.ncbi.nlm.nih.gov/36694358/

Cheng W, Fukuda M, Kim S, Liu Y, Chen X, Holmes C, Li Y, Chung H, Ren Y, Guan J. Osmotically Rupturing Phagosomes in Macrophages Using PNIPAM Microparticles. ACS Appl Mater Interfaces. 2023 May 24;15(20):24244-24256. doi: 10.1021/acsami.3c05335. Epub 2023 May 15. PMID: 37186785; PMCID: PMC10426762.
https://pubmed.ncbi.nlm.nih.gov/37186785/

Carr, D., Sheffler, J., Meynadasy, M., Schmidt, B., Hajcak, G., & Sachs-Ericsson, N. (2023). A longitudinal examination of the protective effect of resilience against anxiety among older adults with high COVID-related worry. Cognitive Behaviour Therapy, 1-19.
https://www.tandfonline.com/doi/full/10.1080/16506073.2023.2191825

Jean Francois, G., Carr, D., Meynadasy, M. A., & Sachs-Ericsson, N. (2023). Prediction of COVID-19-related distress: the role of anxiety and resiliency. Aging & Mental Health, 27(3), 572-579.
https://www.tandfonline.com/doi/full/10.1080/13607863.2022.2084714

Cheng W, Kim S, Zivkovic S, Chung H, Ren Y, Guan J. Specific labelling of phagosome-derived vesicles in macrophages with a membrane dye delivered with microfabricated microparticles. Acta Biomater. 2022 Mar 15;141:344-353. doi: 10.1016/j.actbio.2022.01.028. Epub 2022 Jan 19. PMID: 35063705; PMCID: PMC8898297
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898297/

Sheffler, J.L., Saliga, H., Pickett, S.M. (2022). The role of physical activity on the relationships between pain, anxiety, and sleep quality in older age. Journal of Gerontology: Medical Sciences. DOI: 10.1093/gerona/glac205
https://pubmed.ncbi.nlm.nih.gov/36161473/

Sheffler, J., Arjmandi, B., Hajcak, G., Quinn, J., Vied, C., Akhavan, N., & Naar, S. (2022). Feasibility of an MI-CBT Ketogenic Adherence Program for Older adults with Mild Cognitive Impairment. Pilot and Feasibility Studies, 8(16).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783179/

Schmidt, N.B., Schubert, F.T., Sheffler, J.L. (2022) Brief, Interoceptive Exposure Focused Treatment for Anxiety in Mild Cognitive Impairment: Feasibility of a Brief Anxiety Sensitivity Intervention for MCI Affected Older Adult Dyads. Age & Ageing
https://pubmed.ncbi.nlm.nih.gov/35697353/

Brush, C. J., Kallen, A. M., Meynadasy, M. A., King, T., Hajcak, G., & Sheffler, J. L. (2022). The P300, loneliness, and depression in older adults. Biological Psychology, 171, 108339.
https://www.sciencedirect.com/science/article/am/pii/S0301051122000813

Meynadasy, M. A., Brush, C. J., Sheffler, J., Mach, R., Carr, D., Kiosses, D., ... & Sachs-Ericsson, N. (2022). Emotion regulation and the late positive potential (LPP) in older adults. International Journal of Psychophysiology, 177, 202-212.
https://pubmed.ncbi.nlm.nih.gov/35623475/

Sheffler, J. L., Saliga, H., & Pickett, S. (2022). The role of physical activity on the relationships between pain, anxiety, and sleep quality in older age. The Journals of Gerontology: Series A, glac205.
https://pubmed.ncbi.nlm.nih.gov/36161473/

He, Z., Tian, S., Erdengasileng, A., Hanna, K., Gong, Y., Zhang, Z., ... & Lustria, M. L. A. (2022). Annotation and information extraction of a consumer-friendly health website for enhancing laboratory Test reporting in patient portals. medRxiv, 2022-12.
https://www.medrxiv.org/content/medrxiv/early/2023/04/04/2022.12.19.22283692.full.pdf

Sheffler, J., Meynadasy, M., Taylor, D., Kiosses, D., & Hajcak, G. (2021). Subjective, Neuropsychological, and Neural Markers of Memory in Older Adults. International Psychogeriatrics, 1-9. DOI: 10.1017/S1041610221002623
https://www.cambridge.org/core/journals/international-psychogeriatrics/article/subjective-neuropsychological-and-neural-markers-of-memory-in-older-adults/5EA450C9F6C03C106785B94203C26797#

Sheffler, J., Meyer, C., & Puga, F. (2021). Multi-sample assessment of stress reactivity as a mediator between childhood adversity and mid-to late-life Outcomes. Aging & Mental Health. DOI: 10.1080/13607863.2021.1910787
https://pubmed.ncbi.nlm.nih.gov/33860705/

Luchetti, M., Terracciano, A., Stephan, Y., Aschwanden, D., & Sutin, A. R. (2021). Personality and psychological health in caregivers of older relatives: A case-control study. Aging & Mental Health, 25(9), 1692-1700.
https://www.tandfonline.com/doi/full/10.1080/13607863.2020.1758907

He, Z., Bian, J., Carretta, H. J., Lee, J., Hogan, W. R., Shenkman, E., & Charness, N. (2018). Prevalence of multiple chronic conditions among older adults in Florida and the United States: comparative analysis of the OneFlorida data trust and national inpatient sample. Journal of Medical Internet Research, 20(4), e8961.
https://www.jmir.org/2018/4/e137

He, Z., Gonzalez-Izquierdo, A., Denaxas, S., Sura, A., Guo, Y., Hogan, W. R., Shenkman, E., Bian, J. (2017). Comparing and contrasting a priori and a posteriori generalizability assessment of clinical trials on type 2 diabetes mellitus. In AMIA Annual Symposium Proceedings (Vol. 2017, p. 849). American Medical Informatics Association
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977671/

He, Z., Chen, Z., & Bian, J. (2016, December). Analysis of temporal constraints in qualitative eligibility criteria of cancer clinical studies. In 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (pp. 717-722). IEEE.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733789/