ISL Affiliate Dr. Ravi Nagpal receives three nutrition research grants to advance diet-microbiome research

October 9, 2024

The Institute for Successful Longevity (ISL) at Florida State University is proud to announce that Dr. Ravi Nagpal, Assistant Professor in the Department of Health, Nutrition, and Food Sciences, has been awarded three nutrition research grants to establish and advance his research program focused on the role of diet-microbiome interactions in human health and disease.

Dietary pulses and gut health in young adults:
Pulses, like beans, lentils, and peas, are nutritional powerhouses packed with protein, fiber, and essential nutrients known to be beneficial for gut health. Plus, pulses are low in fat and can be used in a variety of dishes like soups, stews, salads and curries. The fiber in pulses, particularly resistant starch, is partially undigested in the small intestine and reaches the large intestine wherein it fosters the population of beneficial gut bacteria. These bacteria play a crucial role in overall health, from digestion to immunity. However, the specific effects of regular consumption of dietary pulses on specific gut microbes, metabolites, intestinal health features (e.g., gut motility and permeability) and cardiometabolic health markers in young adults remain unknown. Building upon findings from Dr. Nagpal’s preceding USDA-funded project ($240,000), this new USDA-funded research ($300,000) is aimed to understand how consuming dietary pulses can positively impact the gut microbiome, especially in young adults who often lack sufficient fiber intake.

Peanut butter and gut health in school-age children:
Peanuts serve as an excellent source of plant protein, as well as micronutrients such as vitamin E, niacin, magnesium, and iron. Research has shown the individual benefits of each of these nutrients on metabolic health. However, research is lacking on the benefits peanut butter may provide to the gut microbiome and overall gut health, specifically in a younger population where the gut is in a constant state of change. This research funded by The National Peanut Institute ($246,000) aims to establish the role that regular peanut butter consumption plays in promoting and maintaining the health and balance of the gut microbiome in elementary- and middle-school age children.

Effect of watermelon on gut and metabolic health in young adults with overweight or obesity:
Americans often rely on snacks for a significant portion of their daily calories, so snack choices are crucial, especially among college-age students who are always on the run. Watermelon, low in calories and rich in nutrients like vitamin C, lycopene, and L-citrulline, is known to benefit heart health. However, its effect on the gut microbiome is less understood. The gut microbiome is a vital community of microorganisms that affects digestion, immunity, and overall health. This research supported by funding from the National Watermelon Board ($75,000) will investigate how does watermelon consumption modulate the gut microbiome composition and influences heart health in young adults with overweight and obesity.

The Institute for Successful Longevity (ISL) team congratulates Dr. Ravi Nagpal on these impressive research grants. We are excited to see how their work will advance our understanding of diet-microbiome interactions and their impact on health. Wishing you great success in your projects and future endeavors!